Eye-color: multigenic inheritance? incomplete dominance? multiple allelles?

Gary Williams gwilliam at hgmp.mrc.ac.uk
Wed Jan 27 04:24:59 EST 1999


In article <36AEDA01.57EC at my-dejanews.com>,
Steve  <ubiquitous at my-dejanews.com> wrote:
>How is eye-color inherited?

Yes.

>How many genes are implicated in 'producing' the phenotype trait 'eye
>color'?
>Two or more allelles in each gene?

Yes.

>In short, can e.g. two PHENOTYPICALLY blue-eyed humans have a
>phenotypically brown-eyed child?

Yes.

>Is blue eye-color in any sense recessive? And so on.

Yes.

See:

OMIM:227240 EYE COLOR 1; EYCL1
http://www.hgmp.mrc.ac.uk/cgi-bin/wrapomim?227240
CLINICAL SYNOPSIS

Eyes: 
     Blue color recessive to green 

Inheritance: 
     Autosomal recessive at GEY locus;
     Eye color probably polygenic 


OMIM:227220 EYE COLOR 3; EYCL3
http://www.hgmp.mrc.ac.uk/cgi-bin/wrapomim?227220
CLINICAL SYNOPSIS

Eyes: 
     Blue color recessive to brown 

Inheritance: 
     Autosomal recessive at BEY locus;
     Eye color probably polygenic 







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