[Genetic-linkage] Quick Genetics problem help

Dembsky, Joshua Lyman (UMKC-Student) jldxt9 at umkc.edu
Mon May 1 06:40:45 EST 2006


Hello all!
 
I am a graduate student in Kansas City.  I have having some problems understanding a basic genetics concept that I am hoping one of you can help me with.
 
If you have two chromosomes each with an area that has been identified as an area of linkage for a particular trait, what are some of the reasons you can have different lod scores?  For example, if two academic groups have identified an area of linkage of a trait, one study found an area on chromosome 7 with a lod score of 6.00 and another study found an area on chromosome 13 with a lod score of 5.20, how do you explain the different linkage results?
 
Your assistance is greatly appreciated!
jldxt9 at umkc.edu
Josh Dembsky
University of Missouri-Kansas City



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