Oligosaccharide sialylation

Martin Dalziel martin at axford.demon.co.uk
Tue Aug 15 13:50:19 EST 1995


Dear glyco-netters,

Does anyone know of a sialylated N-linked di-antennary oilgosaccharide 
that contains both a2,6 and a2,3 linked sialic acid?
I realise that di-antennarys are usually a2,6 sialylated and, despite
the fact that N-a2,3 sialyltransferase is quite capable of sialylating 
di-antennarys in vitro, FEBS letters 363, 280-284 1995, naturally 
occuring
a2,3 sialylation has so far been confined to tri and tetra-antennary 
structures, but is this is a strict rule or a majority situation?

Martin Dalziel
martin at axford.demon.co.uk





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