Cross-linking glucose to proteins?

[khansh at CCMAIL.APLDBIO.COM]

     The best way to attach Glucose to primary amine is reductive 
     amination.  There are literally thousands of references.  Some common 
     books which are usually found in every library are:
     
     Methods in Enzymology, Vol. 242 and 247
     
     Neoglycoproteins (Eds. Y.C. Lee and R.T. Lee), Academic Press, 1994.
     ISBN 0-12-440585-1
     QP552.G59N46
     
     Advances in Carbohydrate Chemistry and Biochemistry, Vol 37 (1980)
     Chapter by Lee et al., page 225-281
     
     Any undergraduate organic chemistry book will have a section on 
     reductive amination.
     
     Good Luck!
     
     
     -Shaheer Khan-
     Perkin Elmer, Applied Biosystems Division
     Foster City, CA
     


______________________________ Reply Separator _________________________________
Subject: Cross-linking glucose to proteins?
Author:  ingen at Rt66.com at CCMAIL
Date:    5/5/95 10:39 AM


Hi all,
     
I would like to cross-link glucose molecules to carboxyl or primary amino 
groups.  Could somebody suggest reliable methods or refernces?  Thanks.
     
In C. Kim, Ph.D.