Artefacts with PAS-staining?

Robertson Davenport rddvnprt at umich.edu
Fri Oct 20 09:20:16 EST 1995


The PAS stain is based on oxidation of a 1,2 dialcohol to form a 
dialdehyde followed by a double Schiff reaction of sulfate with the 
aldehyde. So if a protein contains, or can be oxidized to, aldehyde 
groups, it may be PAS positive. 

-- 
Robertson D. Davenport, MD
Assistant Professor                    Associate Medical Director
Department of Pathology                Blood Bank and Transfusion Service
University of Michigan Medical School  University of Michigan Hospitals
rddvnprt at umich.edu





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