Concanavalin A

Warren Gallin wgallin at gpu.srv.ualberta.ca
Mon Sep 25 11:03:53 EST 1995


Succinylation will yield a dimer, monovalent forms have been produced by
using a covalent derivatization with an active-site target.
    This was well worked out in the early 70's.  Hit MEDLINE and search
under author names John Wang and Bruce Cunningham; I think it was published
in the Journal of Biological Chemistry.

If you don't want functional monomer, you can of course denature, but I
assume that is not what you want.

Warren Gallin


In Article <43v2cu$iah at mserv1.dl.ac.uk>, Barry Hardy
<bhardy at convex.ox.ac.uk> wrote:
>
>Does anyone know whether Concanavalin A exists as a monomer under very
>specific conditions?
>Someone may have mutated Con A and allowed the naturally occurring 
>tretramer to fall apart.
>



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