Function of secreted glycosyltransferases?

Martin Dalziel martin at axford.demon.co.uk
Tue Jan 23 11:42:58 EST 1996


Dear Glyco-netters,

Various soluble glycosyltransferases are found in serum, colostrum, 
saliva, etc...

I am curious to find out what the consensus of opinion is as to what the 
function(s), if indeed there are any, of these forms of the 
glycosyltransferases might be.

For example, is transferase activity impossible due to the scarcity of 
nucleotide-sugar substrates? Can they still bind to target 
oligosaccharide sequences, without transferase activity, in a lectin 
like manner? or are they simply unwanted secreted cellular products?

Any thoughts out there?  

Martin Dalziel
martin at axford.demon.co.uk





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