IUBio

Activated macrophage markers

Geoff Vince vince at bme.ri.ccf.org
Sun Aug 1 09:45:50 EST 1993


I am currently investigating the role of macrophages in vascular disease.  I 
can successfully identify these cells in paraffin embedded tissue sections 
using anti-CD68 or HAM 56 monoclonal antibodies.  I now wish to find a 
subpopulation that are "activated".  I am currently using anti-HLA-DR alpha 
chain monoclonals as an indicator but would like to know if there was 
anything better.  I have considered using indirect markers such as anti-IL1, 
but would prefer something more tangible.  Has anyone used anti CD25?



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