In article <2arjdtINNps4 at uwm.edu> dpercy at csd4.csd.uwm.edu (Dan S Percy) writes:
> A state of tolerance exists between a mother and its developing
>fetus. What are some of the mechanisms that are thought to be responsible
>for this tolerance. Any comments/suggested readings will be appreciated.
In a recent Immunol. Today (the one with the Rafael-esque) cover, there's an
article about immunity at the fetal-maternal interface, or something to that
effect. Anyway, one of the prevailing hypotheses is that pregnancy shifts
the mother's immune balance towards a Th-2 like state to avoid nasty IFNg-
mediated things like tissue rejection etc, inflammation, etc.
--
Shiv A. Prasad shiv at lenti.med.umn.edu
Dept. of Microbiology pras0005 at student.tc.umn.edu
Univ. of Minnesota
