IgG response elicited by smell

Jerry Woodward woodward at seqanal.mi.uky.edu
Mon Sep 13 12:11:38 EST 1993


Thomas Siepmann (tsiepman at post.its.mcw.edu) wrote:

: When I was an undergrad. at U. of I. (C-U) a few years ago our prof. read
: an article to us about a group that had elicited an IgG response to a
: smell in rats.  First, they immunized the rats while the smelly substance
: was present.  After doing this repeated times, eventually they got a
: specific immune response to the smell alone.  Was wondering if anyone had
: read this journal article and knew where I could find it.  

Smells fishy to me.  You can probably find the article in the circular
file in many immunologists offices.  I remember reading this as well as 
some other "immuno-conditioning" papers and remain underwhelmed.  I have
no trouble believing that one can condition a non-specific response, but I 
think the prospect of conditioning a specific response falls in the same
catagory as cold fusion (IMHO).

J. Woodward
University of Kentucky



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