Inhibiting phagocytosis

Dean Hewish deanh at tigger.mel.dbe.csiro.au
Tue Aug 2 20:56:59 EST 1994


My wife needs to distinguish active phagocytosis from passive
absorbance in human peripheral blood macrophages. She wants to inhibit
phagocytosis in her controls. Cytochalasin-b has been reported to be an
inhibitor of phagocytosis but it doesn't work to 100% in her system (
the cells still take up the particles). Does anyone know if there are
any tricks to using cytochalasin-b and if there are any other agents
that can be used to inhibit phagocytosis?

Dean R. Hewish
Cell biologist and Flow Cytometrist
CSIRO Division of Biomolecular Engineering
Parkville, Victoria, Australia



More information about the Immuno mailing list