Feline Leukemia Information

cheol.yun at usask.ca cheol.yun at usask.ca
Tue Dec 6 02:00:01 EST 1994

You may look at this journal.
Bobade PA, Nash AS & Rogerson P. 1988. Feline haemobartonellosis: 
Clinical, haematological and pathological studies in natural infections 
and the relationship to infection with feline leukaemia virus.
The Veterinary Record 122: 32-36.

I hope this helps.

Cheol H. YUN
yun at sask.usask.ca

On Sat, 3 Dec 1994, Rachel Caspi wrote:

> In article <3bo7oc$imi at newsbf01.news.aol.com>, iclarius at aol.com (IClarius)
> wrote:
> > My son is writing a report for 9th grade biology and needs information on
> > Feline Leukemia. He has reviewed all the library material at school and
> > our local libraries but has only been able to find 3 paragraphs of info.
> > Any info would be greatly appreicated.
> > 
> > thank you,
> > 
> > iclarius
> The following is an excerpt from a FAQ document about cats. Unfortunately,
> it is also 3 paragraphs, but hopefully will add some information to what
> you already have. One more option you might try is a good cat care book,
> available at your local petstore. 
> ------------------------------------------------------------------------------
> G.  Feline Leukemia Virus (FeLV).
> Also a retrovirus, Feline Leukemia is fatal and usually fairly
> quickly, within three to four years and often less.  There is a small
> percentage, ~4%, who are apparently immune and live with FeLV with no
> side effects (except that they are carriers and may infect other
> cats).  There is a vaccination for this disease.
> FeLV is spread mainly by saliva, nose mucous and maybe urine.  It is
> fairly fragile away from cats' bodily fluids,,so transmission by
> humans (on boots, etc.) are not likely.  A latent cat probably needs
> to become viremic (positive test) before it can infect other cats,
> *unless* it is a queen nursing kittens.  The ELISA test has a
> significant false postive rate, depending on fluid tested.  The IFA
> test correlates better with actual virus isolation from tested cats.
> The best way to reduce risk is to keep negative cats away from
> positive cats.
> The virus can affect a lot of tissues, but tends to be most notorious
> for causing cancer of lymphocytes, neutrophiles, platelet precursors,
> in fact nearly all cellular constituants of the blood.  These cancers
> arise from the similar ability to hide out for a long latency in the
> body, but the FeLV virus "irritates" blood forming cells, causing them
> to do strange things (become cancerous).  Very generally, symptoms of
> FeLV infection can range from none (some few recover) to very sick.
> The symptoms depend on which cell line is being attacked.  Treatment
> is similarly complicated, ranging from antivirals to anticancer drugs,
> and other drugs thrown in to manage infections and side effects.
> Immunoregulin has been used with some success in treating cats with
> this disease.
> ------------------------------------------------------------------------------
> -- 
> Rachel R. Caspi, Ph.D.                           phone: 301-496-6409 
> Laboratory of Immunology, NEI                           301-496-6394 
> NIH Building 10, Room 10N222                     fax:   301-402-0485 
> Bethesda, Maryland 20892                 email: rcaspi at helix.nih.gov 

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