nasal investigations

Shiv A. Prasad shiv at hiv.med.umn.edu
Thu Jan 13 22:06:14 EST 1994

In article <2h4pmb$hh at agate.berkeley.edu> frauwirt at mendel.Berkeley.EDU (Ken Frauwirth) writes:
>A similar study (by Trentham et al.), using oral administration of chicken
>type II collagen to tolerize rheumatoid arthritis patients, was published
>in the Sept. 24, 1993 issue of Science. 
>Ken Frauwirth                  BBB   IIIII    OO    K  K   EEEEE   N   N
>frauwirt at mendel.berkeley.edu   B  B    I     O  O   K K    E       NN  N

Oops, that's the one I meant, but I forgot to specify that it was the RA
and not the MS study.  The RA results were a lot more convincing than the 
MS results.  Sort of makes all of those expensive attempts to find Ag-specific
tolerance by inducing clonal anergy or deleting the autoreactive T cells seem
sort of superfluous doesn't it?  Feeding protein from the target tissue is
much cheaper, and doesn't have to be tailored to each patient's MHC alleles.


More information about the Immuno mailing list

Send comments to us at biosci-help [At] net.bio.net