Anti-CD3 for Macaque nemestrina T-cell activation

Michael Robertson michaelr at u.washington.edu
Fri Jan 14 17:37:59 EST 1994


I am trying to study CTL to SIV and HIV in pig-tail macaques (Macaque 
nemestrina).  I would like to develop CTL lines by non-specific 
activation with anti-CD3 similar to what has been done in HIV infected 
humans.  However, OKT3 doesn't seem to work particularly well on macaque 
cells.  Does anyone have a monoclonal that works to acitvate macaque cells?
  Thanks.



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