Self/nonself discrimination

George W Chacko gchacko at magnus.acs.ohio-state.edu
Sun Jul 17 13:10:28 EST 1994


In article <Ct3B5B.DI7 at news.cis.umn.edu>,
Shiv A. Prasad (MicroBio) <shiv at hiv.med.umn.edu> wrote:

>Clonal deletion in the thymus may play the major role in self-nonself 
>discrimination by limiting the number of potentially autoreactive T cells 
>that are exported to the periphery.  

More on the same theme.. Janeway's minireview in Immunity (1994),
1:3-6. Thymic Selection: Two Pathways to Life and Two to Death.

GC

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