HUMAN CTL CULTURE

FOSTERCMD fostercmd at aol.com
Thu Jul 21 16:21:01 EST 1994


Does anybody have good references on serum free formulations and/or
perfusion
system cultures of cloned cytolytic t cells?  I am also preparing a list
of all
known growth factors / interleukins which regulate ctls.   The goal is to
prepare
an efficient perfusion system method of culturing HIV specific human CTLs
to
be used in adoptive immunotherapy.  I believe that current expansion
methods
fail in the ability to maintain physiologically important homing receptors
on the
expanded cells.

Foster P. Carr MD




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