Human IgA

Michael Robertson michaelr at u.washington.edu
Fri Mar 11 14:50:20 EST 1994

In article <del_valle.5.007E73D9 at mpimg-berlin-dahlem.mpg.de>,
Jesus del Valle <del_valle at MPIMG-Berlin-Dahlem.MPG.DE> wrote:
>Hi. I am currently studying the IgA protease of the pathogenic bacterium 
>Neisseria meningitidis. It is known to cleave only human IgA1 and primates 
>IgA therefore I am interested in the following questions: Since they only 
>differ in 20 of the approx. 330 aa comprising the alpha chain, is there a 
>functional difference between both human IgAs (IgA1 and IgA2)?. Do cells 
>expressing them are somehow different or react to different interleukins or 
>anything else?. Do other primates or animals have also two or more IgAs?. 
>Any comments or literature references will be appreciated. Thanks a lot.
>Jesus del Valle    

Does anyone know if US researchers can obtain reagents throught the MRC 
AIDS Reagent Project and/or the ANRS Programme Reactifs SIDA?  If so, 
what is the cost, etc.


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