The header says it all. I am looking for CD4 independent IAk restricted T
cell clones (or hybridomas). I have mutations in IAk that are close to the
suggested CD4 binding site and which block T cell recognition - the most
likely explanations is that they block CD4 binding hence a CD4 independent
clone should still respond. I have a vague recollection of seeing a paper
describing CD4 dependent and independent clones that I thought was from
Adorini's lab, but I haven't been able to track this down. Can anyone
help, either with this paper or with other sources of reagents?
paul
--
Paul J Travers phone : +44-(0)71-631-6262 (office)
ICRF Structural Biology Unit " " " 6268 (lab)
Birkbeck College fax : +44-(0)71-436-8918
Malet Street
London WC1E 7HX email : p_travers at icrf.icnet.uk
England or : paul at histo.cryst.bbk.ac.uk
