IUBio

virtual immunology journal club

FORSDYKE at QUCDN.QueensU.CA FORSDYKE at QUCDN.QueensU.CA
Wed May 25 17:06:11 EST 1994


                                   (J Matthew Buchanan) says:
>
>Is anyone interested in having a virtual journal club?  We could pick a paper
>of general interest say, once a week, or month, then submit posts making
>criticisms, support, refutes, etc.  I think it would liven up the group a
>little and would be a quick and easy way to stay a little more in touch with
>the current literature.

      Your suggestion is something that this forum could do very well!

                      Why don't you start the ball rolling by picking a paper
      for us to read. Preferably a paper in a journal which is widely available
      Give us a couple of weeks to digest. Then give us your two cents worth.
      Then open it up for discussion. The following month, someone else can
      offer to pick one.

                      For new members of the group, I append below our original
     "charter" which set out some of the hopes of Benny Shomer and myself for
      this group.
                      Sincerely,   Don Forsdyke. Discussion Leader
                                                 Bionet.immunology
__________________________________________________________________________

Topics of interest would be:

   Mechanism of self/not-self discrimination
   Evolution and role of MHC polymorphism
   Two signal hypotheses
   Education of T cells
   Education of B cells
   T cell and B cell cooperation
   G0/G1 switch to activate ICCs (immunologically competent cells)
   Mechanisms of ICC deletion or suppression
   T cell receptors
   B cell receptors
   Lymphokines
   Signal transduction pathways
   Complement
   Parasite strategies to avoid the immune response
   Why does not a placental mammal not reject the fetal "graft"
   Relationship of heat-shock response to intracellular self discrimination
   Mechanism of action of cyclosporine
   The acute phase response
   Role of fever in infections- positive or negative?
   Etc.




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