Immunology Questions II

JHR BR jhrbr at
Mon Nov 7 00:15:37 EST 1994

In article <36c5tj$nrb at>, drintoul at (Dave
Rintoul) writes:

>38. What is the key difference between the reaction of antigens with
>antibodies, and reaction of antigens with the T-cell receptor?

>Antigen reaction with the T-cell receptor always occurs at the cell
>surface; the T-cell receptor is always membrane-bound.  Antigen
>reaction with antibodies can occur at the cell surface, but usually
>occurs in solution. Antibodies can be either membrane-bound or

You might also want to mention the necessity for peptide processing, and
presentation with an MHC molecule for antigen reaction with the TCR.

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