Bone Marrow transplant patient immunity questions

jasmith at usuhsb.usuhs.mil jasmith at usuhsb.usuhs.mil
Thu Nov 10 06:58:16 EST 1994


When BMT pts have recovered, how much of their original repertoire of 
ag-specific T-cells, antibodies, etc are regained?  Do they lose immunity
to common antigens, ie, rubella, mumps, viruses, etc?  If so, can they be
reimmunized, given they are immunosuppressed (at least, the allogeneic
transplant recipients)?  And how about surveillance cells, ie, NK, LAK, etc?
Sorry for so many questions, but have found no definitive literature.  



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