greatest immunology discoveries

Esteban Celis cytel1 at
Fri Oct 28 17:34:06 EST 1994

In Article <38mhk9$d0n at>, ejf at
(Ephraim Fuchs) wrote:
>I would like to know what people think is the greatest advance in 
>immunology in the last 25 years.  

What about:

1) the discovery that T-cells recognize protein fragments (peptides) which
bind to MHC molecules?

2) Immunediversity and immunematuration in B cells created by somatic mutation?

3) The structure of T-cell receptor?

4) The cristal structure of MHC

5) Interaction between helper T cells and B cells

6) Thymic negative selection

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