High and low ionic force

Ctro Inmunologia Molecular monoclon%infomed at GN.APC.ORG
Wed Sep 14 12:30:23 EST 1994

   Does anybody know any practical experience in the purification of 
   monoclonal antibody by protein-A chromatography using  buffer 
   systems of high and low ionic force?
   a-Which one is better?
   b-Can I obtain monoclonal antibodies with diferent caracteristics 
   like isoelectric point and estability if I use the same monoclonal 
   with diferent system of purification like the already mentioned ?
Thanks a lot.
monoclon at infomed.sld.cu

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