High and low ionic force

Ctro Inmunologia Molecular monoclon%infomed at GN.APC.ORG
Wed Sep 14 12:30:23 EST 1994


 
 
   Does anybody know any practical experience in the purification of 
 
   monoclonal antibody by protein-A chromatography using  buffer 
 
   systems of high and low ionic force?
 
   
 
   a-Which one is better?
 
   
 
   b-Can I obtain monoclonal antibodies with diferent caracteristics 
 
   like isoelectric point and estability if I use the same monoclonal 
 
   with diferent system of purification like the already mentioned ?
 
 
Thanks a lot.
 
Lobvi
monoclon at infomed.sld.cu
CIM
       
 
   




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