Immunology Questions I

John Ladasky ladasky at leland.Stanford.EDU
Thu Sep 29 09:42:46 EST 1994

In article <36b7jd$4l4 at>,
Ken Frauwirth (BioKen) <frauwirt at notmendel.Berkeley.EDU> wrote:
>Addressing the clustering of Class I and Class II MHC:
>This is probably due less to the "need for diversity" than to the 
>likelihood that the Class I and Class II genes probably arose from gene
>duplication, so they started out clustered.  

	Yet, duplications of other gene families have been found to be 
distributed across multiple chromosomes.  So, you're right, gene dupli-
cation events may tend to be "local" at first.  The question then would
be why the MHC locus "hung together."

Unique ID : Ladasky, John Joseph Jr.
Title     : BA Biochemistry, U.C. Berkeley, 1989
Location  : Stanford University Dept. of Cell Biology, Fairchild D-105
Keywords  : immunology, music, running, Green

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