re cd 8 infection/ hiv not cd4 disease

Ralph M Bernstein ralph at ccit.arizona.edu
Mon Apr 3 09:02:31 EST 1995


ok,
christopher,

    i wonder, do dps in the thymus express the so called co-receptor
"necessary"  for hiv entry? (what is it, cd 36, cd 30?)  i know that that is
under contention now, but perhaps that could help clear up exactly when
_any_ cell with cd4 on its surface is infected, eg, perhaps these cells
cannot be infected intrathymically because they arent expressing that
co-receptor?
    and still i say that there may be a "pipeline" effect (as i said before),
also, has anyone looked to see if dps are actually infected at all?

    food/thought=tired
    regards ralph
Ralph M. Bernstein
Dept of Micro/Immuno
University of Arizona
Ph: 602 626 2585
Fx: 602 626 2100



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