New Immune Theory
Tue Apr 11 14:41:03 EST 1995
In article <3mcrrc$mro at usenetw1.news.prodigy.com>, CVNW83A at prodigy.com (Richard Schultz) says:
What spurs the immune system, Matzinger says, is a shout of "danger" from
>cells dying in distress.
>She ... like other researchers, notes that T-cells
>require a signal from a critical white blood cell, called a dendritic
>cell, before they load their weapons and fire. Dendritic cells inhabit
>every tissue of the body, but they mostly lie dormant.
> To wake them up, cells nearby must call out in shock. "This
>[alert] is the initiation'" Matzinger declared at a recent Cancer
>Research Institute seminar in New York. "Without it, you don't get an
>immune response. Ever."
If this is true, then why can you elicit lymphocyte differentiation and
reproduction to heatkilled novel bacteria, et al.? Or is the response
only one of antibodies? Are B cells differentially elicited?
I'd appreciate your response since I am currently challenging and ranking
individuals' immonoresponsiveness by measuring antibody production to
heatkilled novel bacteria.
R. L. Thompson
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