Sticks in time?

Fred Titmus p.NOrman at umds.ac.UK
Mon Apr 24 06:50:10 EST 1995


        Concerning adhesion marker VLA4. It appears from textboks and 
reviews that I've read that the ligand for VLA4 is VCAM-1. Yet peak 
expression of VCAM on endothelium occurs a few hours after activation, 
whereas VLA is expressed some days later (hence its name!). Does either of 
these molecules have a more important ligand, or is their some other 
mechanism at work?  





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