Induction of peripheral tolerance

Dr. Singh's Lab singhlab at
Mon Aug 21 12:56:16 EST 1995


My impression this debate on tolerance/anergy/apoptosis is quite alive here so 
I have a question of a more practical nature.  Does anyone know of appropriate 
antigen doses (I.V.) to achieve high-zone tolerance in mice?  I am thinking 
more along the lines of older, adult mice where peripheral tolerance would 
more than likely be the mechanism.  Input greatly appreciated.


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