Postdoctoral position in tumor immunology @ UVA

Craig Slingluff, M.D. cls8h at virginia.edu
Fri Aug 25 11:09:16 EST 1995


Postdoctoral position in Tumor Immunology/Immunotherapy

A funded postdoctoral position is available immediately at the
University of Virginia, in Charlottesville, Virginia.

    We have been working primarily on identification of peptide epitopes 
for human melanoma-specific MHC-Class-I-restricted cytotoxic 
T-lymphocytes (JI 150:2955, 1993; Science 1994). A result has been 
identification of an epitope that is being used in a new clinical tumor 
vaccine trial. 

     Ongoing projects include:
(1) identification of additional epitopes from melanoma, 
(2) further characterization of the T-cell response to the       
      melanoma/melanocyte protein Pmel17(gp100), 
(3) investigation of the CTL response to other solid human tumors, and 
(4) investigation of the mechanisms of tumor-associated immune       
      non-responsiveness.  

     The applicant should have a background in cellular immunology, 
should have some experience growing cytotoxic T-cells, and should be 
interested in research at the interface between basic science and human 
clinical applications.  The role of the candidate is negotiable, 
depending on his/her interests and expertise. It would include T-cell 
generation, cellular assays, some molecular genetics, and protein 
chemistry. Collaborations with the laboratories of Vic Engelhard, Ph.D. 
(Microbiology) and Donald Hunt, Ph.D. (chemistry), combined with the 
availability of patients and patient-derived material, provide numerous 
research opportunities.

     Salary would be between $20,000 and $25,000 annually. Travel for 
scientific presentations will be funded by the laboratory.  Funds already 
exist for this position.  
 
     Start: immediately

-- 
Craig L. Slingluff, Jr., M.D.
Associate Professor of Surgery
Chief, Division of Surgical Oncology
University of Virginia Health Sciences Center
cls8h at virginia.edu  ph:(804)924-1505  fax:(804)982-1024





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