Low IgM, ? Signficance

Craig Webster Craig at broombio.demon.co.uk
Wed Dec 13 05:02:29 EST 1995

What is the significance of a low IgM in a 40 year old female ?

What could cause this ?

I have in my mind that:-

1. It could be immuneparesis due to some undetected myeloma
2. It could be due to a IgM cryoglobulin.
3. It could be s selective deficiancy.

Is there anything else it could be ?

I plan to request serum electrophoresis, C3/C4 and collect a proper 
specimen for cryoglobulins. Is there anything else I should be 
considering ?

Craig Webster              |  Tel: 01245 442700
Senior  Clinical Biochemist|  Fax: 01245 514077
Broomfield Hospital        |  email (work) cwebster at broombio.demon.co.uk
Chelmsford, CM1 5ET        |        (home) cwebster at bimbo.demon.co.uk

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