epurcell at UOMHS.edu
Thu Feb 16 15:08:35 EST 1995
In article <9502161255.AA23618 at popserver.jr.cc.gettysburg.edu>, rsorense at GETTYSBURG.EDU (Ralph A. Sorensen) says:
>In preparing a lecture on the functional anatomy of lymphoid tissues, I have
>encountered a question that leaves a hole in my notes: how does
>extravasation of lymphocytes occur in the spleen? All of my sources wax
>eloquent on the role of the HEV in lymph nodes and unencapsulated lymphoid
>tissue, but the only reference I find to the spleen is that there is no HEV!
>To further my confusion, while it is no problem for lymph node lymphocytes
>to return to the circulation via the efferent lymphatics, how do splenic
>lymphocytes return from the white pulp? Could someone help me out and/or
>point me to a reference? Thanks.
>Ralph A. Sorensen
>Biology Department, Gettysburg College
>Gettysburg, PA 17325
>rsorense at gettysburg.edu
>717-337-6168 (voice) 717-337-6157 (fax)
Sonia Carlson at the University of Kentucky has done some nice work on
the role of catecholamines on lymphocyte trafficing in the spleen. You
might try running a medline search for ref's.
University of Osteopathic Medicine and Health Sciences, Des Moines, Iowa
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