HIV and TCell Numbers/Memory

Jorg Kirberg kirberg at
Wed Feb 22 09:45:04 EST 1995

In article <ralph.1143705994A at>, ralph at
(Ralph M Bernstein) wrote:

>it cannot be tcells that havenot
> encountered antigen in the perhiphery, since they die in around 72h after
> release if they dont encounter ag.

A little bit off topic, but it is wrong that naive T cells have a very
limited live span. They have a half-live of more than eight weeks without
dividing ever. Actually it might be even longer depending on the methods
used to find out.

The relevant reference is: J. Exp. Med. 177 (1993): 891.



Joerg Kirberg                     EMAIL: kirberg at
Basel Institute for Immunology    FAX:   41-61-605 13 72
Grenzacherstr. 487                PHONE: 41-61-605 12 77 (lab)
CH-4005 Basel


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