Superantigens

dr. jack komisar dr._jack_komisar at WRSMTP-CCMAIL.ARMY.MIL
Thu Feb 23 08:13:03 EST 1995


             Many superantigens stimulate CD4 and CD8 T cells, even
          though presentation on MHC class II antigens is required for
          a positive reaction in most assay systems.
             Staphylococcal enterotoxin A (SEA) is the most potent T
          cell mitogen known.  As few as 1-5 molecules can activate a
          human T cell.

                                                   Jack Komisar




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