Japan AIDS Patents, May 95

Alan Engel aengel at netaxs.com
Wed Jun 7 14:33:00 EST 1995


The Japanese AIDS-related patent applications 
listed below were published May 1-23, 1995.  
A list of applications published January 1 - 
May 23, 1995 can be found at 

http://www.netaxs.com/~aengel/JapanAIDSPatents/list.htm
____________________________________________

TI= Dibenzocyclooctane compound and drug for 
treating retrovirus infection have it as active ingredient
PA= (000003665) Tsumura KK
IPC= C07D 493/14, A61K 31/36, A61K 31/365, A61K 31/38, C07D407/14, 
C07D493/04, C07D495/14
PN= JP95-112986A
PD= 1995-5-2
AN= JP H5-280722
AD= 1993-10-15
PRN= 
PRD= 
PRC= 
IN= TANAKA Masahide, SAKATA, WAKAMATSU, KAJI Akira, KAJI Hideko
AB= The dibenzocyclooctanes (I) and butyrolactone (II) 
shown below have excellent activity against retroviruses 
such as HIV. 
    (link to image in Web document) where A is one of 
(link to image in Web document)
____________________________________________

TI= Oligonucleotide for detecting cytomegalovirus (CMV) and its 
application
PA= Toyobo Boseki KK
IPC= C12N 15/09, C12Q 1/70
PN=  JP95-111893A
PD=  1995-5-2
AN=  JP H5-260984
AD=  1993-10-19
PRN= 
PRD= 
PRC= 
IN= YAMANISHI, KONDO, AONO, DAIMON
AB= A 15-base oligonucleotide is used to selectively detect CMV 
in supernatants containing various herpes viruses.
____________________________________________

TI= Short chain phosphorothioate bound oligonucleotide
PA= Sankyo KK
IPC= C07H 21/04, A61K 31/70
PN=  JP95-118289A
PD=  1995-5-9
AN=  JP H5-260581
AD=  1993-10-19
PRN= 
PRD= 
PRC= 
IN= AZUMA, MOMOTA, FURUKAWA
AB= The subject compounds below can be used in the treatment and 
prevention of AIDS.  In the formula, n is 1-7, B is an individual 
nucleotide, and X is S or O. 
    (link to image in Web document)
____________________________________________

TI= New thionucleotide intermediate
PA= (000004086) Nihon Kagaku KK
IPC= C07H 19/073, C07H 19/173, A61K 31/70, C07H 5/10
PN=  JP95-126282A
PD=  1995-5-16
AN=  JP H5-293805
AD=  1993-11-1
PRN= 
PRD= 
PRC= 
IN= KAMINISHI Junichi, SEKI, IKEDA Ryuji
AB= The subject compounds display antiviral action against 
HSV-1, HSV-2, HIV, etc, and are expected to be effective 
components in treatment of viral disease.
    (link to image in Web document) In the formula, B is a 
nucleotide, R1 and R3 are H or common protective groups, 
and R2 is lower alkyl of 1-4 carbons.
____________________________________________

TI= Ribozyme expression vector
PA= (000001144) Agency for Industrial Science and Technology
PA= (000004455) Hitachi Chemical Co. Ltd.
PA= (000160522) Hisamitsu Pharmaceutical Co. Inc.
IPC= C12N 15/09
PN=  JP95-123981A
PD=  1995-5-16
AN=  JP H5-277169
AD=  1993-11-5
PRN= 
PRD= 
PRC= 
IN= TABIRA, YUYAMA, OKAWA, TORIYAMA, WADA
AB= Provides a vector which expresses ribozyme which 
reliably cuts the genome RNA of various viruses starting 
with HIV, and expresses RNA which inactivates proteins 
necessary for viral existence and proliferation.
   (link to image in Web document)
____________________________________________

TI= Oligonucleotide for joint and specific detection of 
Epstein-Barr virus (EBV) and cytomegalovirus (CMV)
PA= (000003160) Toyobo Boseki KK
IPC= C12N 15/09, C12Q 1/70
PN=  JP95-123983A
PD=  1995-5-16
AN=  JP H5-273615
AD=  1993-11-1
PRN= 
PRD= 
PRC= 
IN= YAMANISHI, KONDO, AONO, SEGAWA
AB= Provides new oligonucleotide for rapid, reliable 
detection of EBV and CMV.

____________________________________________

TI= Human IL-2 receptor gamma chain molecule
PA= (000000066) Ajinomoto Inc.
PA= (592090832) SUGAMURA Kazuo
IPC= C07K 17/715, A61K 38/00, A61K 39/395, 
C07K 16/28, C12N 15/09, C12P 21/02, G01N 33/53
PN=  JP95-133298A
PD=  1995-5-23
AN=  JP H4-104947
AD=  1992-4-23
PRN= 
PRD= 
PRC= 
IN= SUGAMURA Kazuo, TAKESHITA, ASAO, NAKAMURA, 
SHIMAMURA Yoshiro, SUZUKI Manabu, HAMURO
AB= Invention concerns the IL-2 receptor gamma chain, 
the gene that code for said chain, a vector 
that has said gene, cells transformed by said 
vector, a method for producing the IL-2 receptor 
gamma chain from said cells, an immuno active 
drug containing said chain, and antibodies to 
the IL-2 receptor gamma chain.






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