Inhibition of Apoptosis in T Cells

Carlos A. Gullo cag6p at
Wed Jun 14 19:00:16 EST 1995

	Don't know if this will help you at all (or you may
already be familiar with this info.), but in Jan. 1995 Reed et.
al. in La Jolla demonstrated that tranfection with bag-1 into
Jurkat cells (previously transfected with bcl-2) resulted in
suppression of cell death (actually increased viability) to
anti-Fas mAb and to CTL mediated killing.  However,
tranfection experiments in your condition may not be desirable
or feesible.

Cell, Vol. 80, 279-284, Jan. 1995....John C. Reed

Hope this info. was helpful.

Charles Gullo
Microbilogy Dept.
University of Virginia
Charlottesville, VA 22903
Graduate School of Arts and Sciences
Microbiology Department
University of Virginia
Charlottesville, VA

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