goat and sheep IgG

Bryan Kiehl b3748 at cts.com
Mon Jun 26 17:46:00 EST 1995

In article <1995Jun26.024444.11884 at lugb.latrobe.edu.au>,
   Mick Foley <m.foley at latrobe.edu.au> wrote:
>Hi folks,
>          Can anyone tell me, if I have a monoclonal antibody to goat IgG 
>will it also bind to sheep IgG? (Sheeps and goats are similar, right? 
>well they look similar, right).
>Thanks in advance
>       Mick
If you make a polyclonal antibody against goat it will bind sheep. The odds 
are that this will also be true of monoclonal antibodies, but I'm sure you 
could select clones that do not recognize sheep. However, this may be 
difficult since the cross-reactivity is significant.

Bryan Kiehl
15222-A Avenue of Science
San Diego, CA 92128
(619) 592-9300, ext 309
(619) 592-9400 [FAX]

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