tnf receptors

[Shahram Mori]

(info) (g.luheshi at man.ac.uk) wrote:
: Does anyone know whether rat recombinant TNF-alpha binds to 
: the two different TNF receptors (p55 & P75) with equal affinity in the rat.
A far as I remember the monomers havethe same affinity (1-10nM) but the 
oligomers have different affinities P55 300-500pM and P75 50-100pM.
Cheers
 --
Shahram Mori					   _/\_
Program in Molecular Biology			  _\  /_
Dept. of chemistry and Biochemistry Box 3C	  \_  _/
NMSU  Las Cruces NM				    ||
88003