>>I'm looking for an article in either Nature or Science (I think it
>was?!?) which showed that APCs could present lipid molecules to T-cells.
>From what I remember the lipids were from Mycobacterium (I think!!).
>Does anyone know the reference?
>Please post the response....
>Thanxxxxxxxx.............Big Time
>GV
Dear GV, The reference is
Beckman,EM et al. Nature (1994) 372, 691-694
There was also a news and views.
Evan is in Michael Brenner's lab at Harvard Medical School.
The molecule is CD1b and presents lipids from mycobacterium tuberculosis.
-ed
Edward J. Collins
Department of Molecular and Cellular Biology
Harvard University @@***@@
7 Divinity Ave @@@@*@@@@
Cambridge, MA 02138 @@===@@
phone (617)495-5043 =======
fax (617)495-9613 / \ / \
e-mail collins at xtal220.harvard.edu / + \
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This is supposed to be a class I MHC with a peptide. ---- ----
No wonder my parents suggested Art school was a bad idea.