A question of LPS

Chehebar1 chehebar1 at aol.com
Tue Nov 28 13:29:10 EST 1995


Hello,

I am a graduate student working on a paper that involves cellular
activation in response to lipopolysaccharide, and I am not sure as to how
this stuff gets phagocytosed. Does it have to be bound with IgG (i.e.,
opsonized), or can a macrophage just decide it doesn't like the looks of
it and do a non-specific phagocytosis? If the latter is true, what
receptors if any are involved in recognizing LPS in the medium? I am
specifically interested in the Fc-gamma RI,II, and III receptors. 

TIA, 
Dan Chehebar



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