Help on Natural Killer Cells

David Peritt Peritt_d at a1.mscf.upenn.edu
Mon Sep 18 10:32:15 EST 1995


In article <43hvho$70j at cocoa.brown.edu> Gary C. Pien, Gary_Pien at brown.edu
writes:
>specific T cell receptor (TCR) 

  
>Thus, the target specificity of NK cells is greater than that for CTLs. 

Why is target specificity greater in NK over CTL's?  So how do NK cells
know self from foreign?  The negative signaling of the class I like
recognition structures is an interesting begginning.



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