What is the prime (') in F(ab)'2

Mårten Schneider marten.schneider at immun.uu.se
Wed Sep 20 04:16:58 EST 1995

In article <43ml4m$nma at netnews.upenn.edu>, David Peritt
<Peritt_d at a1.mscf.upenn.edu> wrote:

> I TA an undergrad Immunology and the proffessor was stumped by the
> history behind the prime in the nomenclature for f(ab)'2 and Fab'.  Can
> anyone shed light on this??

Fab fragments containing the heavy chain hinge are called Fab'. If the
interchain disulfide bonds are intact, the two Fab' fragments remain
associated and are called F(ab')2.
Mårten Schneider, Dept. of Medical Immunology and Microbiology, Uppsala, Sweden.
(Marten.Schneider at immun.uu.se)

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