Signal transduction by ClassI MHC

Ingrid Jakobsen ingrid at helios.anu.edu.au
Fri Sep 22 23:48:37 EST 1995


In article <43tij7$hon at owl.und.ac.za>, kelso at beastie.cs.und.ac.za (Janet Kelso) writes:
|> I was wondering if any research has been done on whether or not the 50
|> kilodalton cytoplasmic domain of the class I MHC plays a role in signal
|> transduction. If so, what is the outcome of the signal?
|> 
|> Just interested...anyone got any ideas?

All I know is there's a Tyr which can be phosphorylated by 
pp60(v-src) and is quite conserved.
(Guild et al  PNAS 80: 2894-98  1983)
Does anyone know if this was followed up or if anything else 
has been done since?

Ingrid


**************************************
Ingrid Jakobsen at anu.edu.au           
Human Genetics Group                  
John Curtin School of Medical Research
Australian National University.	
P.O. Box 334   Canberra, ACT 2601      



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