MLC

Jes Dietrich vader at biobase.dk
Tue Apr 16 03:19:33 EST 1996


I have a question about MLC. I hope somebody can help me with it.

In a "one way" MLC you measure the proliferative respons of responder cells to stimulatory cells.
But exactly which cells is it that are proliferating?
And which type of cells are the stimulating cells?
Are the responder cells memory T cells or the naive T cells (or both). In the latter case they would require 
a co-stimulatory signal (B7) which I suppose they could get from the stimulator MØ and/or 
dendritic cells.

Best regards
Jes Dietrich



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