Need H-2 restricted Antigens

Tom Thatcher ttha at uhura.cc.rochester.edu
Thu Apr 18 12:05:02 EST 1996

I need some antigens that raise T cell immunity in mice that are H-2k
but not H-2b, and in H-2b but not H-2k.  If you know of such antigens
or useful references, please point them out.

Some caveats:
I know about the WEHI database of MHC binding peptides.  Unfortunately,
it doesn't tell me which MHC a peptide *doesn't* bind, only which ones
it does; and it doesn't say whether a certain protein raises a vigorous
response or an undetecable response that still raised a few clonable cells.

I would prefer whole proteins that are readily available so I don't have 
to synthesize peptides (I need less than 1 mg so why waste a whole batch)

Thanks in advance for any input.

Tom Thatcher                          | You can give a PC to a Homo habilis,
University of Rochester Cancer Center | and he'll use it, but he'll use it
ttha at uhura.cc.rochester.edu           | to crack nuts.

More information about the Immuno mailing list

Send comments to us at biosci-help [At] net.bio.net