antibodies to rat l-selectin

[Aaron Warnock]

In article <4ctqc2$he6 at mserv1.dl.ac.uk>,
Catherine Derry <c-derry at nimr.mrc.ac.uk> wrote:
>Does anyone have or know of blocking antibodies to rat L-selectin that
>don't induce clustering of lymphocytes?
>Thanks in advance for any help .
>Cath. Derry

What exactly do you mean by "clustering"? Cross-linking L-selectin
usually leads to shedding, but not cellular activation/aggregation (eg
integrin avidity up-regulation...)

Anyway, you can check the Hybridoma Resource Data Base at 

	gopher://culture.atcc.org:70/77/newindices.dev/HDB-DI-INDEX

for source info and to find things like:

   1015094 RE 1.G>Rattus rattus 1.CN>black rat 1.SN>L-selectin

  AN 1015094
  DI P>Harlan Bioproducts
  DI 2.P>Seikagaku America Inc.
  DE P>HRL3 ;distributor
  DE P>MCA-1092 ;distributor
  DE 2.C>HRL3 ;distributor
  IM G>Rattus rattus CN>black rat SN>L-selectin a.CC>differentiation
  IM b.CC>genetically engineered
  DO G>Cricetulus migratorius CN>Armenian hamster O>lymph node
  PD ;IgG
  RE 1.G>Rattus rattus 1.CN>black rat 1.SN>L-selectin
  RE 1.FS>functional epitope 1.a.CC>differentiation
  AP ;flow cytometry
  AV ;purified
  SD HRL3
  SD MCA1092
  LD USA JMJ
  EI DA>9405 
  CI ;catalog 

Also, you can always medline search for articles and call up the
people who've got the stuff you want...

Later,

Aaron
-- 
"Nothing more is needed to destroy a man, than the conviction that his
life's work is useless."  -Antonin Artaud

awarnock at cmgm.stanford.edu (R. Aaron Warnock)