IUBio

OVERLOOKED VACCINE APPROACH?

Harold Bien hbien at jhunix.hcf.jhu.edu
Tue Jan 9 20:04:49 EST 1996


Cohl+Santoni (ncrf at ix.netcom.com) wrote:
: A vaccine can be made from a person's own cells. Such vaccines have been the
: object of much cancer research. Has there been any research into using such
: vaccines to fight HIV? I have not been able to find any references.

	I believe that HIV mutates its protien coat relatively rapidly, 
hence making the efficacy of immunotherapy questionable.  However, I've 
heard that several researchers are looking into common glycoprotiens on 
HIV in an attempt to create anti-HIV antibodies.
	Also, I've read somewhere (sorry, no references available) that 
it HIV infection does not occur without an immunologic response.  On the 
contrary, it seems that the immune system mounts a vigorous response 
against HIV but is ultimately defeated by the rate of production of HIV 
and other factors (eg. mutation of protien coat).
	I'm no expert, however, and this is only a surmise on my part.



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