IUBio

RANTES

Aaron Warnock awarnock at cmgm.stanford.edu
Sat Jan 20 17:34:51 EST 1996


Howdy,

In article <4dq1im$kic_001 at kkuhn.pennet.net>,
Keith R. Kuhn <kkuhn at pennet.net> wrote:

>Until recently, all known chemokines could be placed into 
>two biochemical superfamilies.  These families could be 
...
>chemokine family and the C-C amino acid structures the  
>-chemo-kines.   RANTES are produced by T cells and act 
...

These families are generally called either "C-C" or "C-X-C".

>OK, what I would like to know, is from where is the term 
>"rantes" derived.  What does it stand for?  I run into this 
>problem of technical jargon may times when scanning the 
>journals and usually my references will provide a 
>clarification.  Here they have failed my.  Thanks for any 
>help you care to provide.


Hmm... technical jargon... I think you'll laugh at this...
My (authoratative ) sources say:

RANTES is the character from some film... the editors at JI said
something like: "Hey, this ain't fruitfly stuff, call it something
serious." So, they sat down (with the proper stumulents for thought)
and realized that RANTES really meant something like: Regulated (upon)
Activation (of) Normal T (cell) Expression (and presumably) Secreted.

So y'all can put that down in your immuno-lore diary.

Later,

Aaron


-- 
"Nothing more is needed to destroy a man, than the conviction that his
life's work is useless."  -Antonin Artaud

awarnock at cmgm.stanford.edu (R. Aaron Warnock)



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