In article <698301476wnr at djpritch.demon.co.uk>,
David John Pritchard <Dave at djpritch.demon.co.uk> wrote:
>>I want to freeze dry antibodies (particularly in plasma from people
>with autoimmune diseases), as a means of long term storage. In my
>attempts so far I have frequently seen a significant drop in titre
>either immediately upon freeze drying or after a couple of months
>storage at 2-8 degrees C.
>>Does anybody have any experience of successfully freeze drying
>antibodies, and if so any advice on suitable protocols, additives to
>enhance stability etc. would be very welcome.
>>Thanks
>>Dave
>>Dave:
Could you send your lyophilization and storage procedures so that I
could review them. Maybe I could spot something that could
be changed or improved.
Les
