Thalidomide

Bayu_Prawira bayu at euronet.nl
Sat Jan 27 11:20:26 EST 1996


In article <M_Doherty-2301961804010001 at db45.niaid.nih.gov> M_Doherty at NIH.gov (M. Doherty) writes:
>From: M_Doherty at NIH.gov (M. Doherty)
>Subject: Thalidomide
>Date: Tue, 23 Jan 1996 23:04:01 GMT

>Dear Colleagues,

>No, not another chain of scare messages!  I am working on a project
>involving activation of HIV in transgenic mice.  We have shown that
>infection by a number of different organisms induces virus transcription
>and that NF-KB appears to be essential.  Since thalidomide has been shown
>to downregulate TNF-a production (another factor dependant on NF-KB), we
>would like to look at thalidomide in this system.

>Can anyone tell me where we might be able to get our hands on some?

>Please respond either here or to my address (mdoherty at pop.niaid.nih.gov).

>Thanks for your help.

>Cheers, Mark

Thalidomide in some countries is still being used for type 2 reaction of 
Leprosy. You can try to contact some dermatologists dealing with Leprosy to 
find out. Or you may try to contact the manufacturer that produced it long 
time ago, maybe they still have some in their stocks.

Bayu P. Hie, MD



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