quinine activity

Kiley R. Prilliman kprillim at rex.re.uokhsc.edu
Tue Jun 4 21:25:23 EST 1996


Quinolones are only effective (by the mechanism previously described) in 
bacteria; quinine (which is usually used to treat chloroquine-resistant 
Plasmodium falciparum) is a different agent (an alkaloid) which blocks 
DNA synthesis by intercalating into dsDNA and thereby preventing DNA 
synthesis.



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